The purpose of this research paper is to examine the role of human resource relative to their specific role in organizational job design at managerial and operational levels for achieving sustainable competitive advantage. Variable taken in this study included human capital and job design as independent and sustainable competitive advantage as dependent variable while management expertise was taken as intervening variable. The data gathering instrument used for the research was questionnaire and interviews. For conducting the present study an empirical research on 100 respondents of banking sector were considered. Regression technique was used to analyze research problem and for conducting data analysis. The findings of the study showed that human resource capabilities contribute positively related with organizational performance. Research also revealed that it totally depends on the managerial expertise rather than individual capabilities towards achievement of organizational competitive advantage. Furthermore, management expertise was found to be a significant predictor for achieving sustainable competitive advantage. Organizational management plays an important role to achieve higher performance from their employees by strategically deploying them according to their skills, interests and passion